Cell Science and Molecular Biology

Molecular Pathology and Diagnostics

Molecular pathology and diagnostics refer to the study and analysis of disease at the molecular level to understand the underlying mechanisms and develop diagnostic tools and treatments. It involves the use of molecular biology techniques to examine biomarkers, genetic mutations, and other molecular changes associated with disease.In molecular pathology, researchers and clinicians study how genes and proteins are altered in disease states. This includes identifying mutations, deletions, and other changes in the DNA or RNA of cells. By understanding these molecular changes, researchers can develop molecular tests to diagnose diseases more accurately and guide treatment decisions.Molecular diagnostics is the application of molecular biology techniques to diagnose disease. This can include the use of polymerase chain reaction (PCR) to detect the presence of specific DNA or RNA sequences associated with disease, or the use of next-generation sequencing (NGS) to analyze the entire genome or transcriptome of a patient. These tests can provide more precise and personalized information about a patient's disease, leading to more targeted and effective treatments.